The product utilizes an F gene-deleted Sendai virus vector carrying reprogramming factors.
Key features include:
No infection risk during use
Simplified single-vial operation
High iPS cell induction efficiency (compatible with multiple cell types)
Rapid viral clearance post-delivery.
MeltonVEC™-Sendai iPSC Reprogramming Kit is designed for the efficient reprogramming of somatic cells into induced pluripotent stem cells (iPSCs), providing a stable and controllable reprogramming process. The kit is compatible with a broad range of starting cell types, including peripheral blood mononuclear cells (PBMCs) and T cells, enabling the generation of iPSC lines from donors with diverse genetic backgrounds.
As a highly efficient, non-integrating iPSC reprogramming solution, the MeltonVEC™ kit combines high reprogramming efficiency, streamlined operation, and rapid vector clearance, making it suitable for establishing high-quality iPSC lines from various somatic cell sources.
The MeltonVEC™- Sendai iPSC Reprogramming Kit has been successfully applied to the following somatic cell types:
MeltonVEC™-Sendai iPSC Reprogramming Kit
| Specification | Details |
|---|---|
| Vector Type | Non-integrating RNA viral vector |
| Typical Reprogramming Efficiency | 0.05–1% |
| Genomic Integration | No |
| Blood Cell Reprogramming | Yes. Compatible with multiple blood-derived cell types, including CD34⁺ cells, peripheral blood mononuclear cells (PBMCs), and T cells |
| Special Equipment Required | None |
| Reprogramming Factors | OCT4, SOX2, KLF4, and c-MYC |
| Residual Vector Detection | qPCR |
| Storage Conditions | −80°C |
| Shelf Life | 12 months |
| Item | Description |
|---|---|
| Catalog Number | MSV1001-1 |
| Recommended Application | PBMC reprogramming |
| Package Size | 3 vials, 60 μL per vial |
| KOSM | KLF4, OCT3/4, c-MYC, and SOX2 |
| KOS | KLF4, OCT3/4, and SOX2 |
| c-MYC | c-MYC vector |
| Item | Description |
|---|---|
| Catalog Number | MSV1001-2 |
| Recommended Application | Fibroblast reprogramming |
| Package Size | 3 vials, 60 μL per vial |
| KOS | KLF4, OCT3/4, and SOX2 |
| c-MYC | c-MYC vector |
| KLF4 | KLF4 vector |